Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773648 | 0.92 | TLR7 (0.48) | TLR7TLR8NUDT1 | |
| SCHEMBL6773147 | 0.90 | TLR7 (0.45) | TLR7TLR8NUDT1 | |
| SCHEMBL6775141 | 0.86 | TLR7 (0.51) | TLR7TLR8NUDT1DRD2DRD3 | |
| SCHEMBL6768441 | 0.85 | TLR7 (0.47) | TLR7TLR8KDM4ENUDT1 | |
| SCHEMBL6774879 | 0.85 | TLR7 (0.48) | TLR7TLR8HPGDKDM4ELMNA | |
| SCHEMBL6779814 | 0.85 | FAAH (0.47) | TLR7TLR8LMNAHDAC1HDAC8 | |
| SCHEMBL6772264 | 0.83 | TLR7 (0.45) | TLR7TLR8HPGDKDM4ELMNA | |
| SCHEMBL6286196 | 0.83 | TLR7 (0.45) | TLR7TLR8NUDT1DRD2DRD3 | |
| SCHEMBL6777954 | 0.82 | TLR7 (0.41) | TLR7TLR8HPGDKDM4EGAA | |
| SCHEMBL6772297 | 0.82 | TLR7 (0.44) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |