SCHEMBL6771954

SCHEMBL6771954

Cc1cc(-c2scc3ccccc23)c(C)cc1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 4/20 0.38
HPGD P15428 3/20 0.38
HSD17B10 Q99714 3/20 0.38
MEN1 O00255 2/20 0.38
NPC1 O15118 2/20 0.38
KMT2A Q03164 2/20 0.38
PKM P14618 1/20 0.38
USP2 O75604 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
RAB9A P51151 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 4/20 0.37
CYP2A6 P11509 3/20 0.36
TSHR P16473 3/20 0.35
CYP3A4 P08684 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16600442 0.80 ALDH1A1 (0.39) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL17059022 0.78 CYP1A2 (0.42) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL6313115 0.76 CYP2A6 (0.48) ALDH1A1HPGDHSD17B10NPC1USP2
SCHEMBL28092298 0.74 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL15048643 0.73 CYP2A6 (0.54) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL13261664 0.71 ALDH1A1 (0.43) ALDH1A1MAPTHPGDHSD17B10CASP1
SCHEMBL12128629 0.69 ALOX5 (0.42) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL20837440 0.69 ALDH1A1 (0.37) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL26087020 0.69 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL21253810 0.67 ALDH1A1 (0.58) ALDH1A1KDM4EMAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696487-B2 FOR COMBATING THE PHYTOPATHOGENIC FUNGI OF CROPS BAYER CROPSCIENCE S.A. (FR) 2004-02-24 US disclosed
US-20030008884-A1 Fungicidal phenyl (thio) urea and phenyl (thio) carbamate derivatives AVENTIS CROPSCIENCE S.A. 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008884-A1 Fungicidal phenyl (thio) urea and phenyl (thio) carbamate derivatives NAT1, CAT, TPMT ALDH1A1 1599/4885KDM4E 640/4885MAPT 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.