Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773884 | 0.96 | TP53 (0.43) | KDM4EHSD17B10ALDH1A1TSHRTP53 | |
| SCHEMBL6096076 | 0.88 | TLR7 (0.45) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL6773388 | 0.86 | TLR7 (0.37) | KDM4EHPGDHSD17B10ALDH1A1TP53 | |
| SCHEMBL6096657 | 0.85 | LMNA (0.39) | SMN1; SMN2 | |
| SCHEMBL6779205 | 0.84 | TLR7 (0.43) | KDM4EHPGDHSD17B10ALDH1A1TP53 | |
| SCHEMBL6779797 | 0.84 | BRD4 (0.36) | MAPT | |
| SCHEMBL6773525 | 0.84 | TLR7 (0.41) | — | |
| SCHEMBL6778890 | 0.83 | TLR7 (0.40) | KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL6779395 | 0.83 | TLR7 (0.46) | ALDH1A1HTR1ADRD2DRD4TP53 | |
| SCHEMBL6286213 | 0.82 | HTT (0.46) | KDM4EHPGDHSD17B10USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |