Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847822 | 0.74 | LPAR3 (0.43) | CYP1A2HPNFGFR1MEN1KMT2A | |
| SCHEMBL8511047 | 0.70 | PDE4B (0.62) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5846757 | 0.68 | HPN (0.49) | HPNFGFR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5848942 | 0.66 | PDE4B (0.43) | HPNMEN1KMT2AALDH1A1POLB | |
| SCHEMBL2651119 | 0.66 | TSHR (0.61) | CYP1A2ALDH1A1SMN1; SMN2CYP2C9HPGD | |
| SCHEMBL296300 | 0.66 | TSHR (0.61) | CYP1A2ALDH1A1SMN1; SMN2CYP2C9HPGD | |
| SCHEMBL27484245 | 0.65 | FGFR1 (0.50) | HPNFGFR1MEN1KMT2AALDH1A1 | |
| SCHEMBL3535123 | 0.65 | GPR35 (0.54) | CYP1A2MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL2532656 | 0.64 | TSHR (0.59) | CYP1A2ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL10771123 | 0.64 | MAPK14 (0.56) | CYP1A2HPNMEN1KMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716838-B1 | INHIBITORS OF SERINE PROTEASES OF THE COAGULATION CASCADE | PHARMACIA CORPORATION | 2004-04-06 | — | — | US | disclosed |