Sugi Predict

Sugi Predict / Compounds / SCHEMBL296300

SCHEMBL296300

SCHEMBL296300

O=C(O)Cc1cccc([N+](=O)[O-])c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.61
▸ ALDH1A1 P00352 4/20 0.59
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ TP53 P04637 1/20 0.56
▸ LMNA P02545 2/20 0.55
▸ CYP1A2 P05177 2/20 0.54
▸ HTT P42858 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ CES2 O00748 1/20 0.53
▸ CES1 P23141 1/20 0.53
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ SIGMAR1 Q99720 2/20 0.52
▸ ALOX15 P16050 1/20 0.52
▸ HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2651119 1.00 TSHR (0.61) TSHRALDH1A1SMN1; SMN2TP53LMNA
Hydrochloric Acid SCHEMBL2532656 0.98 TSHR (0.59) TSHRALDH1A1SMN1; SMN2TP53LMNA
Formic Acid SCHEMBL28148811 0.94 TSHR (0.54) TSHRALDH1A1SMN1; SMN2TP53LMNA
SCHEMBL1694325 0.88 TSHR (0.59) TSHRALDH1A1SMN1; SMN2TP53LMNA
SCHEMBL28977512 0.86 ALDH1A1 (0.64) TSHRALDH1A1SMN1; SMN2TP53LMNA
SCHEMBL11362791 0.86 TSHR (0.61) TSHRALDH1A1SMN1; SMN2TP53LMNA
SCHEMBL48947 0.84 TSHR (0.59) TSHRALDH1A1SMN1; SMN2TP53LMNA
SCHEMBL7723429 0.84 TSHR (0.59) TSHRALDH1A1SMN1; SMN2TP53LMNA
SCHEMBL2082576 0.84 TSHR (0.59) TSHRALDH1A1SMN1; SMN2TP53LMNA
SCHEMBL641742 0.84 TSHR (0.64) TSHRALDH1A1SMN1; SMN2TP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1038 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP claimed
WO-2025243208-A2 PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF HOVIONE - FARMACIÊNCIA, SA (PT) 2025-11-27 — — WO claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 — — WO claimed
CN-114351144-B Gold etching solution 湖北兴福电子材料股份有限公司 2023-06-02 — — CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 — — US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 — — US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 — — US claimed
WO-2014087006-A1 METHOD AND DEVICE FOR ADMINISTERING HYPOXIC AND HYPEROXIC GAS CELLGYM TECHNOLOGIES GMBH (DE) 2014-06-12 — — WO claimed
EP-2223952-B1 Adhesive formulations TYCO HEALTHCARE (US) 2012-05-09 — — EP claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 — — US claimed
EP-1255806-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 — — EP claimed
US-20020011584-A1 Stable, aqueous compositions for treating surfaces, especially fabrics THE PROCTOR & GAMBLE COMPANY 2002-01-31 — — US claimed
US-20020010154-A1 Compositions comprising cyclodextrin THE PROCTER & GAMBLE COMPANY 2002-01-24 — — US claimed
WO-2001088076-A1 COMPOSITIONS COMPRISING CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 2001-11-22 — — WO claimed
US-6289286-B1 Surface regeneration of biosensors and characterization of biomolecules associated therewith BIACORE AB (SE) 2001-09-11 — — US claimed
WO-2001060961-A1 STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS THE PROCTER & GAMBLE COMPANY (US) 2001-08-23 — — WO claimed
EP-1082607-A1 SURFACE REGENERATION OF BIOSENSORS Biacore AB (SE) 2001-03-14 — — EP claimed
WO-1999063333-A1 SURFACE REGENERATION OF BIOSENSORS BIACORE AB (SE) 1999-12-09 — — WO claimed
EP-0582929-A1 Process for the preparation of aminophenylacetates HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-16 — — EP claimed
EP-0055616-A1 Antibacterial compounds BEECHAM GROUP PLC (GB) 1982-07-07 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS TSHR 1605/4885ALDH1A1 3087/4885SMN1; SMN2 4271/4885
US-20020010154-A1 Compositions comprising cyclodextrin FFAR4, FRG1, FGB TSHR 3607/4885ALDH1A1 3053/4885SMN1; SMN2 4007/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS TSHR 1605/4885ALDH1A1 3087/4885SMN1; SMN2 4271/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS TSHR 1605/4885ALDH1A1 3087/4885SMN1; SMN2 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.