Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772178 | 0.87 | MAPK14 (0.54) | MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL6768792 | 0.84 | SRC (0.60) | MAPK14MAPK11CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL6772362 | 0.81 | MAPK14 (0.49) | MAPK14MAPK11CA1CA2CA4 | |
| SCHEMBL6779368 | 0.81 | SRC (0.60) | MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL6774270 | 0.81 | MAPK14 (0.47) | MAPK14MAPK11CSNK1DMAPK13MAPK12 | |
| SCHEMBL6623278 | 0.81 | SRC (0.58) | PTGS2MAPK14MAPK11ALOX5SMN1; SMN2 | |
| SCHEMBL6771371 | 0.81 | SRC (0.62) | MAPK14MAPK11ALOX5MAPK13MAPK12 | |
| SCHEMBL6774561 | 0.81 | MAPK14 (0.63) | MAPK14MAPK11ALOX5CSNK1A1CSNK1D | |
| SCHEMBL6773296 | 0.81 | MAPK14 (0.57) | MAPK14MAPK11ALOX5CSNK1ESMN1; SMN2 | |
| SCHEMBL6772797 | 0.78 | MAPK14 (0.54) | MAPK14MAPK11ALDH1A1ALOX5CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1505625-A | Triazole compounds useful in treating diseases associated with unwanted cytokine activity | — | 2004-06-16 | — | — | CN | claimed |
| US-6727364-B2 | ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY | 2004-04-27 | — | — | US | claimed |
| US-20030013712-A1 | Triazole compounds useful in treating diseases associated with unwanted cytokine activity | PROCTER & GAMBLE COMPANY, THE | 2003-01-16 | — | — | US | claimed |
| US-6727364-B2 | ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY | 2004-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013712-A1 | Triazole compounds useful in treating diseases associated with unwanted cytokine activity | IL4, IL1A, IL2 | PTGS2 798/4885PTGS1 388/4885MAPK14 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.