SCHEMBL677238

SCHEMBL677238

COc1cc(C)c(C(=O)Cl)c(OC)c1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
HPGD P15428 3/20 0.42
KMT2A Q03164 3/20 0.42
POLB P06746 2/20 0.42
CYP3A4 P08684 2/20 0.42
MEN1 O00255 2/20 0.42
GFER P55789 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 4/20 0.42
HTT P42858 2/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.42
HTR1A P08908 1/20 0.42
HTR2C P28335 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ACHE P22303 1/20 0.42
LMNA P02545 2/20 0.41
CYP19A1 P11511 2/20 0.40
NQO2 P16083 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27813524 0.85 ACHE (0.45) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL677571 0.83 HPGD (0.54) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL11044236 0.81 CYP3A4 (0.35) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL12587644 0.81 POLB (0.57) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL677167 0.77 MAPT (0.40) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL6149583 0.77 CYP3A4 (0.46) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL7519964 0.76 KRAS (0.47) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL676688 0.76 MAPT (0.39) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL7943881 0.76 ATM (0.54) MAPTHPGDKMT2APOLBCYP3A4
SCHEMBL6148942 0.76 TUBB4A (0.44) MAPTNPSR1ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA (JP) 2017-07-06 US disclosed
US-9655362-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-05-23 US disclosed
CN-103478142-B The method of control of microbicide compositions and plant disease ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-03-30 CN disclosed
EP-1679003-B1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA (JP) 2015-04-15 EP disclosed
CN-101215260-B Method for preparing benzoylpyridine derivatices and salt thereof ISHIHARA SANGYO KAISHA 2014-07-09 CN disclosed
US-8653113-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-02-18 US disclosed
US-8653277-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2014-02-18 US disclosed
CN-103478142-A Bactericide composition and method of controlling plant disease ISHIHARA SANGYO KAISHA 2014-01-01 CN disclosed
US-8609150-B2 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-12-17 US disclosed
CN-102165961-B Bactericide composition and method of controlling plant disease ISHIHARA SANGYO KAISHA 2013-10-23 CN disclosed
CN-102165961-A Bactericide composition and method of controlling plant disease ISHIHARA SANGYO KAISHA 2011-08-31 CN disclosed
EP-2338335-A1 Preparation of fungicidal benzoylpyridine derivatives ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-06-29 EP disclosed
CN-101822253-A The method of control of microbicide compositions and plant disease ISHIHARA SANGYO KAISHA 2010-09-08 CN disclosed
CN-100581362-C Bactericide composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA 2010-01-20 CN disclosed
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-10-01 US disclosed
CN-101215260-A Method for preparing benzoylpyridine derivatices and salt thereof ISHIHARA SANGYO KAISHA (JP) 2008-07-09 CN disclosed
CN-101199274-A Bactericide composition and method for controlling plant disease ISHIHARA SANGYO KAISHA (JP) 2008-06-18 CN disclosed
CN-1874680-A bactericide composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA (JP) 2006-12-06 CN disclosed
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-08-31 US disclosed
EP-1679003-A1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CBR1, CNPY2 MAPT 4140/4885HPGD 1354/4885KMT2A 2040/4885
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases CBR3, CNPY2, PAH MAPT 4366/4885HPGD 1278/4885KMT2A 2575/4885
US-20170188579-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CNPY2, PAH MAPT 4366/4885HPGD 1278/4885KMT2A 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.