Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772875 | 0.72 | ALDH1A1 (0.38) | ALDH1A1ATMMAPK1RAB9AKMT2A | |
| Bromide SCHEMBL5978880 | 0.67 | ALDH1A1 (0.38) | ALDH1A1ATMMAPK1RAB9AKMT2A | |
| SCHEMBL5071273 | 0.66 | CTNNB1 (0.45) | ALDH1A1RAB9AKMT2AKDM4EGAA | |
| Bromide SCHEMBL3843813 | 0.65 | CTNNB1 (0.44) | ALDH1A1RAB9AKMT2AKDM4EGAA | |
| SCHEMBL30990025 | 0.65 | KMT2A (0.48) | ALDH1A1ATMMAPK1RAB9AKMT2A | |
| SCHEMBL5071291 | 0.65 | GAA (0.46) | ALDH1A1ATMMAPK1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL3848956 | 0.64 | GAA (0.46) | ALDH1A1ATMMAPK1RAB9AKMT2A | |
| SCHEMBL13280179 | 0.63 | HPGD (0.74) | ALDH1A1MAPK1RAB9AKDM4EGAA | |
| SCHEMBL26125381 | 0.63 | HPGD (0.74) | ALDH1A1MAPK1RAB9AKDM4EGAA | |
| SCHEMBL10067347 | 0.62 | TSHR (0.64) | ALDH1A1ATMMAPK1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790859-B2 | THERAPY OR REDUCING PROGRESSION OF HYPERTENSION OR DAMAGE TO A TISSUE CAUSED BY CONTACT WITH ELEVATED LEVELS OF REDUCING SUGARS IN AN ANIMAL, COMPRISING ADMINISTERING TO THE ANIMAL AN EFFECTIVE AMOUNT OF THIAZOLIUM COMPOUNDS | ALTEON INCORPORATED | 2004-09-14 | — | — | US | claimed |