Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CPT1A | P50416 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5978880 | 0.84 | ALDH1A1 (0.38) | ALDH1A1ATMRAB9AMAPK1MAPT | |
| Bromide SCHEMBL7050720 | 0.81 | ALDH1A1 (0.36) | ALDH1A1ATMRAB9AMAPK1MAPT | |
| Hydrochloric Acid SCHEMBL3848955 | 0.80 | HPGD (0.44) | ALDH1A1ATMRAB9AMAPK1CHRM2 | |
| SCHEMBL5071288 | 0.79 | HPGD (0.45) | ALDH1A1ATMRAB9AMAPK1CHRM2 | |
| SCHEMBL5071273 | 0.77 | CTNNB1 (0.45) | ALDH1A1RAB9AKMT2AKDM4ENPC1 | |
| Bromide SCHEMBL3843813 | 0.76 | CTNNB1 (0.44) | ALDH1A1RAB9AKMT2AKDM4ENPC1 | |
| Bromide SCHEMBL5015757 | 0.75 | KMT2A (0.44) | ALDH1A1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL6772878 | 0.72 | ALDH1A1 (0.43) | ALDH1A1ATMRAB9AMAPK1MAPT | |
| SCHEMBL5071271 | 0.71 | KMT2A (0.52) | ALDH1A1RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL5071291 | 0.71 | GAA (0.46) | ALDH1A1ATMRAB9AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790859-B2 | THERAPY OR REDUCING PROGRESSION OF HYPERTENSION OR DAMAGE TO A TISSUE CAUSED BY CONTACT WITH ELEVATED LEVELS OF REDUCING SUGARS IN AN ANIMAL, COMPRISING ADMINISTERING TO THE ANIMAL AN EFFECTIVE AMOUNT OF THIAZOLIUM COMPOUNDS | ALTEON INCORPORATED | 2004-09-14 | — | — | US | claimed |