Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763628 | 0.86 | GAA (0.44) | SMN1; SMN2POLBGAAPKMALDH1A1 | |
| SCHEMBL12322297 | 0.86 | GAA (0.53) | SMN1; SMN2POLBGAAPKMALDH1A1 | |
| SCHEMBL6767865 | 0.76 | MAPT (0.53) | MEN1KMT2ACYP1A2HPGDMAPK1 | |
| SCHEMBL31543727 | 0.70 | AHR (0.44) | SMN1; SMN2MEN1KMT2ALMNATP53 | |
| SCHEMBL7679788 | 0.70 | MEN1 (0.44) | SMN1; SMN2MEN1KMT2ALMNATP53 | |
| SCHEMBL4866368 | 0.70 | MAPT (0.43) | SMN1; SMN2MEN1KMT2AMAPK1POLB | |
| SCHEMBL13397872 | 0.70 | CA12 (0.61) | KMT2ALMNAHPGDMAPK1NPSR1 | |
| SCHEMBL5393113 | 0.69 | GAA (0.59) | SMN1; SMN2MEN1KMT2APOLBGAA | |
| SCHEMBL1507659 | 0.69 | MEN1 (0.40) | SMN1; SMN2MEN1KMT2ALMNATP53 | |
| SCHEMBL6767845 | 0.69 | MAPT (0.60) | MEN1KMT2ALMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |