Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.76 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FRK | P42685 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771889 | 0.86 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL6772108 | 0.86 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL6772126 | 0.85 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6772944 | 0.83 | MAPK14 (0.77) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL6773691 | 0.82 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL6769729 | 0.79 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL6768638 | 0.79 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL6773358 | 0.77 | MAPK14 (0.74) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL6772165 | 0.75 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11MAP4K4 | |
| SCHEMBL6772401 | 0.75 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1505625-A | Triazole compounds useful in treating diseases associated with unwanted cytokine activity | — | 2004-06-16 | — | — | CN | claimed |
| US-6727364-B2 | ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY | 2004-04-27 | — | — | US | claimed |
| US-20030013712-A1 | Triazole compounds useful in treating diseases associated with unwanted cytokine activity | PROCTER & GAMBLE COMPANY, THE | 2003-01-16 | — | — | US | claimed |
| US-6727364-B2 | ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY | 2004-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013712-A1 | Triazole compounds useful in treating diseases associated with unwanted cytokine activity | IL4, IL1A, IL2 | MAPK14 3429/4885MAPK13 4097/4885MAPK12 4447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.