Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769678 | 0.83 | POLB (0.42) | ALDH1A1HTTPOLB | |
| SCHEMBL6110335 | 0.77 | KDM4E (0.39) | ALDH1A1GAACNR2CNR1 | |
| SCHEMBL6773855 | 0.76 | KDM4E (0.43) | ALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6774577 | 0.76 | TSHR (0.44) | ALDH1A1SMN1; SMN2LMNAPOLB | |
| Hydrochloric Acid SCHEMBL6110768 | 0.76 | KDM4E (0.38) | ALDH1A1GAACNR2CNR1 | |
| SCHEMBL6779590 | 0.75 | MAPKAPK2 (0.43) | ALDH1A1SMN1; SMN2HTTLMNAGAA | |
| SCHEMBL6776398 | 0.74 | KDM4E (0.36) | ALDH1A1SMN1; SMN2HTTLMNAGAA | |
| SCHEMBL6782569 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL6777928 | 0.74 | MEN1 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTPOLB | |
| SCHEMBL6283619 | 0.74 | TLR7 (0.32) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |