Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778424 | 0.82 | TLR7 (0.37) | NPC1RAB9AALDH1A1TLR8 | |
| SCHEMBL6773855 | 0.77 | KDM4E (0.43) | KDM4ECYP3A4NPC1HTTLMNA | |
| SCHEMBL6777224 | 0.77 | EPHX1 (0.37) | KDM4ECYP3A4HSD17B10ALDH1A1KMT2A | |
| SCHEMBL6768462 | 0.76 | TLR7 (0.38) | HSD17B10KMT2ASMN1; SMN2TLR8 | |
| SCHEMBL6779590 | 0.76 | MAPKAPK2 (0.43) | CYP3A4NPC1RAB9AHTTLMNA | |
| SCHEMBL6776668 | 0.76 | SMN1; SMN2 (0.44) | KDM4ENPC1RAB9AHTTLMNA | |
| SCHEMBL6110335 | 0.75 | KDM4E (0.39) | KDM4ECYP3A4MAPK1ALDH1A1GAA | |
| SCHEMBL6283619 | 0.74 | TLR7 (0.32) | ALDH1A1GAA | |
| SCHEMBL6773229 | 0.74 | EPHX2 (0.46) | HTTLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6779314 | 0.74 | QPCT (0.45) | LMNAALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |