Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283993 | 0.82 | HTT (0.41) | KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6782528 | 0.81 | HPGD (0.42) | KDM4EKMT2AMEN1HPGDDUSP3 | |
| SCHEMBL6776398 | 0.77 | KDM4E (0.36) | KDM4EKMT2AMEN1CYP3A4NPC1 | |
| SCHEMBL6773229 | 0.76 | EPHX2 (0.46) | LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6288799 | 0.76 | HTT (0.44) | KDM4EKMT2AMEN1HPGDLMNA | |
| SCHEMBL6779590 | 0.76 | MAPKAPK2 (0.43) | KMT2AMEN1CYP3A4NPC1CYP2C19 | |
| SCHEMBL6110335 | 0.75 | KDM4E (0.39) | KDM4EHPGDCYP3A4CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6110768 | 0.74 | KDM4E (0.38) | KDM4EHPGDCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL4792956 | 0.73 | HTT (0.41) | KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6782569 | 0.73 | SMN1; SMN2 (0.44) | KDM4EKMT2AMEN1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |