⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625097 | 0.83 | — | — | |
| SCHEMBL6620220 | 0.80 | — | — | |
| SCHEMBL6623188 | 0.77 | L3MBTL1 (0.32) | — | |
| SCHEMBL6622047 | 0.75 | RAB9A (0.34) | — | |
| SCHEMBL6623140 | 0.74 | L3MBTL1 (0.32) | — | |
| SCHEMBL6891052 | 0.71 | — | — | |
| SCHEMBL6624731 | 0.71 | L3MBTL1 (0.34) | — | |
| SCHEMBL6624443 | 0.66 | DPP8 (0.34) | — | |
| SCHEMBL7722492 | 0.66 | ELANE (0.37) | — | |
| SCHEMBL7731889 | 0.65 | ELANE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825187-B2 | CARBAPENEM DERIVATIVES SUBSTITUTED AT THE 2-POSITION WITH A SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP; USE AGAINST ANTIBIOTIC RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA, ENTEROCOCCI AND INFLUENZA VIRUS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-11-30 | — | — | US | disclosed |