Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12682901 | 0.83 | CHRNA7 (0.44) | CHRNA7CHRNB2CHRNA4CCR5MAPT | |
| SCHEMBL6767869 | 0.82 | CHRNA7 (0.61) | CHRNA7CHRNB2CHRNA4CCR5PABPC1 | |
| SCHEMBL20017727 | 0.81 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4CCR5MAPT | |
| SCHEMBL1961848 | 0.81 | APOBEC3A (0.48) | CHRNA7CHRNB2CHRNA4CCR5MAPT | |
| SCHEMBL17853861 | 0.81 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4CCR5MAPT | |
| Hydrochloric Acid SCHEMBL15259648 | 0.80 | CHRNA7 (0.39) | CHRNA7CHRNB2CHRNA4CCR5MAPT | |
| SCHEMBL6770769 | 0.80 | CHRNA7 (0.45) | CHRNA7CHRNB2CHRNA4CCR5USP2 | |
| Hydrochloric Acid SCHEMBL10751415 | 0.79 | APOBEC3A (0.47) | CHRNA7CHRNB2CHRNA4CCR5MAPT | |
| SCHEMBL10257015 | 0.79 | APOBEC3A (0.47) | CHRNA7CHRNB2CHRNA4CCR5MAPT | |
| Bromide SCHEMBL10751445 | 0.79 | APOBEC3A (0.47) | CHRNA7CHRNB2CHRNA4CCR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825187-B2 | CARBAPENEM DERIVATIVES SUBSTITUTED AT THE 2-POSITION WITH A SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP; USE AGAINST ANTIBIOTIC RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA, ENTEROCOCCI AND INFLUENZA VIRUS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030022881-A1 | Novel carbapenem derivatives of quarternary salt type | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
| EP-1251134-A1 | NOVEL CARBAPENEM DERIVATIVES OF QUATERNARY SALT TYPE | MEIJI SEIKA KAISHA LTD. (JP) | 2002-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022881-A1 | Novel carbapenem derivatives of quarternary salt type | DHPS, HDHD5, RRP15 | CHRNA7 4408/4885CHRNB2 4501/4885CHRNA4 3735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.