Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.45 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 10/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813478 | 0.92 | CDYL (0.64) | KDM4ECDYLHTR2ACYP3A4MEN1 | |
| Oxalic Acid SCHEMBL3811985 | 0.81 | KDM4E (0.49) | KDM4ECDYLCYP3A4ALDH1A1TDP1 | |
| Oxalic Acid SCHEMBL3810442 | 0.81 | KDM4E (0.49) | KDM4ECDYLHTR2ACYP3A4MEN1 | |
| SCHEMBL1180012 | 0.79 | ADRB2 (0.58) | KDM4ECDYLHTR2ACYP3A4MEN1 | |
| SCHEMBL1180543 | 0.78 | ADRB2 (0.59) | KDM4ECDYLHTR2ACYP3A4MEN1 | |
| SCHEMBL3807751 | 0.78 | HTR1B (0.55) | KDM4ECDYLHTR2AMEN1KMT2A | |
| SCHEMBL7808904 | 0.77 | CDYL (0.63) | KDM4ECDYLHTR2ACYP3A4MEN1 | |
| SCHEMBL8721975 | 0.77 | CDYL (0.61) | KDM4ECDYLHTR2ACYP1A2CYP2D6 | |
| Oxalic Acid SCHEMBL3807723 | 0.77 | KDM4E (0.49) | KDM4ECYP3A4ALDH1A1TDP1CYP1A2 | |
| SCHEMBL586305 | 0.77 | CYP1A2 (0.52) | CDYLTDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |