Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809768 | 0.93 | CYP19A1 (0.43) | KDM4ECDYLLMNAALDH1A1CHRM2 | |
| Oxalic Acid SCHEMBL3810442 | 0.81 | KDM4E (0.49) | KDM4ECDYLLMNAALDH1A1CHRM2 | |
| Oxalic Acid SCHEMBL6773522 | 0.81 | KDM4E (0.72) | KDM4ECDYLLMNAALDH1A1CHRM2 | |
| SCHEMBL3817882 | 0.80 | OPRM1 (0.45) | CYP19A1TBXAS1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL3815960 | 0.79 | OPRM1 (0.46) | CYP19A1TBXAS1OPRM1OPRK1 | |
| SCHEMBL3812607 | 0.79 | OPRM1 (0.41) | ALDH1A1TSHRCYP19A1TBXAS1OPRM1 | |
| SCHEMBL48683 | 0.77 | POLB (0.46) | CYP19A1TBXAS1OPRM1OPRK1 | |
| SCHEMBL3813019 | 0.77 | ALDH1A1 (0.45) | KDM4ELMNAALDH1A1CYP19A1TBXAS1 | |
| Oxalic Acid SCHEMBL3808260 | 0.76 | STING1 (0.39) | KDM4ELMNAALDH1A1CHRM2CHRM1 | |
| Oxalic Acid SCHEMBL3808502 | 0.76 | KDM4E (0.38) | KDM4ECDYLLMNAALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |