Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21690129 | 1.00 | SIRT2 (0.49) | SIRT2ALPIPKMPTGS1XIAP | |
| SCHEMBL3839522 | 1.00 | SIRT2 (0.49) | SIRT2ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL6326997 | 0.99 | SIRT2 (0.48) | SIRT2ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL27994024 | 0.99 | SIRT2 (0.48) | SIRT2ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL21176269 | 0.99 | SIRT2 (0.48) | SIRT2ALPIPKMPTGS1XIAP | |
| SCHEMBL21095860 | 0.94 | KIF11 (0.48) | SIRT2ALPIPKMPTGS1XIAP | |
| SCHEMBL21095861 | 0.93 | KIF11 (0.49) | SIRT2KIF11 | |
| SCHEMBL31404225 | 0.91 | SIRT2 (0.48) | SIRT2KIF11CPB1CPB2 | |
| SCHEMBL21096113 | 0.90 | KIF11 (0.52) | SIRT2KIF11 | |
| SCHEMBL522051 | 0.86 | SIRT2 (0.60) | SIRT2KIF11CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024316-A | 2, 4-binitro-6-phenyl-phenylthio protecting group and polypeptide synthesis method thereof | 南开大学 | 2023-11-10 | — | — | CN | claimed |
| EP-3970796-B1 | COMPOSITION FOR PREVENTING OR TREATING NEUROTROPHIC KERATITIS WHICH CONTAINS STABILIZED PACAP PEPTIDE | SENJU PHARMA CO (JP) | 2025-08-20 | — | — | EP | disclosed |
| US-12304932-B2 | PACAP stabilized peptide | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2025-05-20 | — | — | US | disclosed |
| CN-111344300-B | Stabilizing peptides of PACAP | 千寿制药株式会社 | 2024-08-30 | — | — | CN | disclosed |
| US-20240200049-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS | YALE UNIVERSITY | 2024-06-20 | — | — | US | disclosed |
| US-20240140935-A1 | NON-COVALENT DIMER CATION, SALT THEREOF, PREPARATION METHOD THEREOF, AND USE THEREOF AS ANTIOXIDANT | SUZHOU PROTONATION CHAIN BIOTECHNOLOGY CO., LTD. (CN) | 2024-05-02 | — | — | US | disclosed |
| CN-117024316-A | 2, 4-binitro-6-phenyl-phenylthio protecting group and polypeptide synthesis method thereof | 南开大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-110746355-B | Phenylpyrazole compound, pharmaceutical composition, and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2023-08-11 | — | — | CN | disclosed |
| US-11649446-B2 | Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids | YALE UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |
| CN-116082565-A | Self-assembled oxidation mimic enzyme material and preparation method and application thereof | 北京化工大学 | 2023-05-09 | — | — | CN | disclosed |
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | LES LABORATOIRES SERVIER (FR) | 2003-03-20 | — | — | US | disclosed |
| US-5830868-A | Substituted DI- and tripeptide inhibitors of protein: farnesyl transferase | WARNER-LAMBERT COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| US-5763577-A | ANTICARCINOGENIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0767800-A1 | HISTIDINE AND HOMOHISTIDINE DERIVATIVES AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0730605-A1 | SUBSTITUTED DI- AND TRIPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0725790-A1 | SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE | PARKE DAVIS & COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1996017861-A1 | SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1996-06-13 | — | — | WO | disclosed |
| WO-1996000736-A1 | HISTIDINE AND HOMOHISTIDINE DERIVATIVES AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |
| WO-1995012612-A1 | SUBSTITUTED DI- AND TRIPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1995-05-11 | — | — | WO | disclosed |
| WO-1995011917-A1 | SUBSTITUTED TETRA- AND PENTAPEPTIDE INHIBITORS OF PROTEIN:FARNESYL TRANSFERASE | PARKE, DAVIS & COMPANY (US) | 1995-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12304932-B2 | PACAP stabilized peptide | VIP, DNPEP, SCTR | SIRT2 2759/4885ALPI 4217/4885PKM 3059/4885 |
| US-20240140935-A1 | NON-COVALENT DIMER CATION, SALT THEREOF, PREPARATION METHOD THEREOF, AND USE THEREOF AS ANTIOXIDANT | SLC10A1, CYP11B1, CYP11B2 | SIRT2 728/4885ALPI 903/4885PKM 1245/4885 |
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | MME, ACE, ECE1 | SIRT2 3453/4885ALPI 3216/4885PKM 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.