Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | F2 | P00734 | 18/20 | 1.00 |
| ▸ | CTRB1 | P17538 | 3/20 | 1.00 |
| ▸ | F9 | P00740 | 2/20 | 1.00 |
| ▸ | F5 | P12259 | 2/20 | 1.00 |
| ▸ | PROC | P04070 | 1/20 | 0.99 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Razaxaban SCHEMBL29376499 | 1.00 | F10 (1.00) | F10F2CTRB1F9F5 | |
| Razaxaban SCHEMBL29456625 | 0.99 | F10 (1.00) | F10F2CTRB1F9F5 | |
| Razaxaban SCHEMBL6885838 | 0.99 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL6493125 | 0.94 | F10 (0.88) | F10F2CTRB1F9F5 | |
| SCHEMBL5376245 | 0.92 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL6503086 | 0.91 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL6198725 | 0.91 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL6197266 | 0.91 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL5386162 | 0.91 | F10 (1.00) | F10F2CTRB1F9F5 | |
| SCHEMBL12589578 | 0.89 | F10 (1.00) | F10F2CTRB1F9F5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991638-B1 | NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2005-08-17 | — | — | EP | claimed |
| US-20020025963-A1 | Novel guanidine mimics as factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-02-28 | — | — | US | claimed |
| US-6339099-B1 | FOR THERAPY AND PROPHYLAXIS OF THROMBOEMBOLIC DISORDER | DUPONT PHARMACEUTICALS COMPANY | 2002-01-15 | — | — | US | claimed |
| US-10478459-B2 | Compositions and methods for cell transplantation | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2019-11-19 | — | — | US | disclosed |
| US-20170354723-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | PROMETHERA BIOSCIENCES S.A. (BE) | 2017-12-14 | — | — | US | disclosed |
| US-20170354723-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | PROMETHERA BIOSCIENCES S.A. (BE) | 2017-12-14 | — | — | US | disclosed |
| US-20170319542-A1 | PHARMACEUTICAL COMPOSITION CONTAINING GINKGOLIDE B AND XA FACTOR INHIBITOR, PREPARATION METHOD THEREOF AND USE THEREOF | CHENGDU BAIYU PHARMACEUTICAL CO., LTD (CN) | 2017-11-09 | — | — | US | disclosed |
| US-9775890-B2 | Factor Xa inhibitor used with liver-derived progenitor cells | Université Catholique de Louvain (BE) | 2017-10-03 | — | — | US | disclosed |
| US-9775890-B2 | Factor Xa inhibitor used with liver-derived progenitor cells | Université Catholique de Louvain (BE) | 2017-10-03 | — | — | US | disclosed |
| US-20150037291-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2015-02-05 | — | — | US | disclosed |
| US-20150037291-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2015-02-05 | — | — | US | disclosed |
| WO-2004031143-A3 | NOVEL COMBINATION OF A FACTOR XA INHIBITOR AND CLOPIDOGREL | BRISTOL MYERS SQUIBB CO (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004031143-A2 | NOVEL COMBINATION OF A FACTOR XA INHIBITOR AND CLOPIDOGREL | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |
| WO-2004031143-A2 | NOVEL COMBINATION OF A FACTOR XA INHIBITOR AND CLOPIDOGREL | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |
| WO-2004031143-A2 | NOVEL COMBINATION OF A FACTOR XA INHIBITOR AND CLOPIDOGREL | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |
| US-20040067995-A1 | Novel combination of a factor Xa inhibitor and clopidogrel | BRISTOL-MYERS SQUIBB COMPANY | 2004-04-08 | — | — | US | disclosed |
| US-20040063772-A1 | Novel intermediates for guanidine mimics as factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-04-01 | — | — | US | disclosed |
| US-20030069258-A1 | Novel guanidine mimics factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-04-10 | — | — | US | disclosed |
| US-20020025963-A1 | Novel guanidine mimics as factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-02-28 | — | — | US | disclosed |
| US-6339099-B1 | FOR THERAPY AND PROPHYLAXIS OF THROMBOEMBOLIC DISORDER | DUPONT PHARMACEUTICALS COMPANY | 2002-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170354723-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | SERPINC1, F13B, F12 | F10 7/4885F2 9/4885CTRB1 27/4885 |
| US-20030069258-A1 | Novel guanidine mimics factor Xa inhibitors | TFPI, F11, F12 | F10 8/4885F2 11/4885CTRB1 235/4885 |
| US-10478459-B2 | Compositions and methods for cell transplantation | SERPINC1, F13B, F12 | F10 7/4885F2 9/4885CTRB1 27/4885 |
| US-20170319542-A1 | PHARMACEUTICAL COMPOSITION CONTAINING GINKGOLIDE B AND XA FACTOR INHIBITOR, PREPARATION METHOD THEREOF AND USE THEREOF | F13B, VKORC1, VKORC1L1 | F10 13/4885F2 25/4885CTRB1 38/4885 |
| US-20040063772-A1 | Novel intermediates for guanidine mimics as factor Xa inhibitors | TFPI, SERPINC1, F11 | F10 13/4885F2 19/4885CTRB1 291/4885 |
| US-20150037291-A1 | COMPOSITIONS AND METHODS FOR CELL TRANSPLANTATION | SERPINC1, F13B, F12 | F10 8/4885F2 10/4885CTRB1 26/4885 |
| US-20040067995-A1 | Novel combination of a factor Xa inhibitor and clopidogrel | F11, F12, SERPINC1 | F10 12/4885F2 11/4885CTRB1 58/4885 |
| US-20020025963-A1 | Novel guanidine mimics as factor Xa inhibitors | F11, SERPINC1, TFPI | F10 11/4885F2 18/4885CTRB1 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.