Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415440 | 0.90 | F10 (0.49) | AKT1SMN1; SMN2F10ALOX15RAB9A | |
| SCHEMBL6413590 | 0.82 | AKT1 (0.45) | AKT1F10 | |
| Hydrochloric Acid SCHEMBL7455665 | 0.81 | AKT1 (0.47) | AKT1SMN1; SMN2F10CDK2ALOX15 | |
| SCHEMBL7360451 | 0.80 | AKT1 (0.47) | AKT1F10 | |
| SCHEMBL6773814 | 0.79 | F10 (0.47) | SMN1; SMN2F10ALOX15MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6712997 | 0.78 | F10 (0.48) | AKT1SMN1; SMN2F10 | |
| SCHEMBL7357796 | 0.77 | F10 (0.44) | SMN1; SMN2F10ALOX15RAB9A | |
| SCHEMBL5756624 | 0.77 | KDR (0.54) | AKT1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL7362082 | 0.76 | F10 (0.47) | SMN1; SMN2F10ALOX15RAB9A | |
| SCHEMBL7359916 | 0.75 | F10 (0.44) | AKT1SMN1; SMN2F10ALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140905-A1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039117-A1 | HETEROROAROMATIC AMIDES AS INHIBITOR OF FACTOR Xa | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |