SCHEMBL677407

SCHEMBL677407

CNc1ccc(Oc2cccc(Oc3ccc(NC(=O)c4cccc(C(=O)Nc5ccc(O)c(NC(=O)c6cccc(C(C)=O)c6)c5)c4)cc3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.54
AR P10275 1/20 0.53
HDAC3 O15379 2/20 0.48
BRAF P15056 2/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC7 Q8WUI4 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC10 Q969S8 2/20 0.48
HDAC11 Q96DB2 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
HDAC9 Q9UKV0 2/20 0.48
HDAC5 Q9UQL6 2/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
RAB9A P51151 1/20 0.48
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108328 0.97 AR (0.53) PGRARHDAC3BRAFHDAC4
SCHEMBL676656 0.97 AR (0.53) PGRARHDAC3BRAFHDAC4
SCHEMBL677388 0.90 AR (0.47) PGRARHDAC3BRAFHDAC4
SCHEMBL677399 0.87 KDR (0.44) PGRARHDAC3BRAFHDAC4
SCHEMBL13657052 0.86 KMT2A (0.61) PGRARNPC1ALDH1A1RAB9A
SCHEMBL13329058 0.86 AR (0.53) PGRARHDAC3BRAFHDAC4
SCHEMBL1108314 0.85 KCNMA1 (0.52) HDAC1HDAC2HDAC8HDAC6NPC1
SCHEMBL13321798 0.85 AR (0.58) PGRARHDAC3BRAFHDAC4
SCHEMBL13321803 0.84 AR (0.59) PGRARHDAC3BRAFHDAC4
SCHEMBL10309801 0.84 AR (0.57) PGRARHDAC3BRAFHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7906213-B2 Epoxy resin curable composition for prepreg ADEKA CORPORATION (JP) 2011-03-15 US disclosed
US-20090030147-A1 Epoxy Resin Curable Composition For Prepreg ADEKA CORPORATION (JP) 2009-01-29 US disclosed