Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14885955 | 0.83 | TMPRSS4 (0.74) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL30472745 | 0.83 | TMPRSS4 (0.74) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL1998921 | 0.82 | F10 (0.60) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL5395436 | 0.82 | SMN1; SMN2 (0.66) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL3151641 | 0.80 | SORT1 (0.61) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL6592032 | 0.80 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL2989305 | 0.79 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL13235136 | 0.78 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL2433512 | 0.77 | POLB (0.67) | RAB9ANPC1SMN1; SMN2HTTALOX15 | |
| SCHEMBL6261356 | 0.77 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2HTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689780-B1 | PYRIDINE DERIVATIVES | ELI LILLY AND COMPANY | 2004-02-10 | — | — | US | disclosed |
| EP-1140905-B1 | HETEROAROMATIC AMIDES AS INHIBITOR OF FACTOR XA | LILLY CO ELI (US) | 2003-05-14 | — | — | EP | disclosed |