⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441470 | 0.81 | — | — | |
| SCHEMBL8159751 | 0.79 | TSHR (0.48) | — | |
| SCHEMBL1781150 | 0.77 | — | — | |
| SCHEMBL233906 | 0.77 | TSHR (0.38) | — | |
| SCHEMBL231380 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL235149 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL17628431 | 0.75 | — | — | |
| SCHEMBL235272 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL874045 | 0.75 | — | — | |
| SCHEMBL6909579 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9694214-B2 | Preparation of silicone microemulsions | DOW CORNING CORPORATION (US) | 2017-07-04 | — | — | US | disclosed |
| US-8344087-B2 | Hydrosilylation cured organosiloxanes having diluent therein | DOW CORNING CORPORATION (US) | 2013-01-01 | — | — | US | disclosed |
| US-8153724-B2 | Organosiloxane compositions | DOW CORNING CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20120016063-A1 | HYDROSILYLATION CURED ORGANOSILOXANES HAVING DILUENT THEREIN | DOW SILICONES CORPORATION | 2012-01-19 | — | — | US | disclosed |
| US-8067519-B2 | Organosiloxane compositions | DOW CORNING CORPORATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110165206-A1 | Preparation of Silicone Microemulsions | DOW SILICONES CORPORATION | 2011-07-07 | — | — | US | disclosed |
| US-20100093598-A1 | Silicone Foam Control Agent | DOW CORNING EUROPE SA (BE) | 2010-04-15 | — | — | US | disclosed |
| US-20090234052-A1 | Organosiloxane Compositions | DOW SILICONES CORPORATION | 2009-09-17 | — | — | US | disclosed |
| US-20080312367-A1 | Organosiloxane Compositions | DOW SILICONES CORPORATION | 2008-12-18 | — | — | US | disclosed |
| EP-0620258-B1 | Radiation-curable poly(alpha-olefin) adhesives containing pendant olefinic functionality | MINNESOTA MINING & MFG (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0620258-A2 | Radiation-curable poly(alpha-olefin) adhesives containing pendant olefinic functionality | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-19 | — | — | EP | disclosed |