SCHEMBL8159751

SCHEMBL8159751

C=CCCCCCC[Si](C)(C)C=C

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
ALDH1A1 P00352 4/20 0.40
ABCC4 O15439 1/20 0.37
MAPT P10636 1/20 0.37
LMNA P02545 2/20 0.36
TRPA1 O75762 2/20 0.34
TDP1 Q9NUW8 2/20 0.33
USP2 O75604 1/20 0.33
HPGD P15428 1/20 0.33
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909579 0.87
SCHEMBL17628450 0.87
SCHEMBL17628431 0.84
SCHEMBL30890195 0.80 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL6673537 0.80 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL29236761 0.80 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL31135174 0.80 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL29381466 0.80 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL29384354 0.80 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL29381599 0.80 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250043045-A1 METHOD FOR PREPARING LONG-CHAIN BRANCHED POLYPROPYLENE NATIONAL CHUNG CHENG UNIVERSITY (TW) 2025-02-06 US claimed
EP-3768687-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP claimed
EP-3768686-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies, LLC (US) 2021-01-27 EP claimed
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US claimed
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-07 US claimed
CN-112074525-A Silicon-terminated organometallic compounds and methods for making the same 陶氏环球技术有限责任公司 2020-12-11 CN claimed
CN-112004818-A Silicon-terminated organometallic compounds and methods of making the same 陶氏环球技术有限责任公司 2020-11-27 CN claimed
WO-2019182988-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
WO-2019182983-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO claimed
US-20250043045-A1 METHOD FOR PREPARING LONG-CHAIN BRANCHED POLYPROPYLENE NATIONAL CHUNG CHENG UNIVERSITY (TW) 2025-02-06 US disclosed
US-20250043045-A1 METHOD FOR PREPARING LONG-CHAIN BRANCHED POLYPROPYLENE NATIONAL CHUNG CHENG UNIVERSITY (TW) 2025-02-06 US disclosed
EP-3768687-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
EP-3768733-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
EP-3768686-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies, LLC (US) 2021-01-27 EP disclosed
US-5407970-A Peel adhesion, cohesive strength at elevated temperatures MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US disclosed
EP-0416921-B1 Radiation curable polyolefin pressure-sensitive adhesive MINNESOTA MINING & MFG (US) 1995-01-18 EP disclosed
EP-0620258-A2 Radiation-curable poly(alpha-olefin) adhesives containing pendant olefinic functionality MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-10-19 EP disclosed
US-5209971-A Radiation curable polyolefin pressure sensitive adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-11 US disclosed
US-5112882-A Alpha-olefin polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-05-12 US disclosed
EP-0416921-A1 Radiation curable polyolefin pressure-sensitive adhesive MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002308-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME SCAMP2, SOD1, SCLY TSHR 4805/4885ALDH1A1 1828/4885ABCC4 1471/4885
US-20210002315-A1 SILICON-TERMINATED ORGANO-METAL COMPOUNDS AND PROCESSES FOR PREPARING THE SAME SIK1, SIK2, MCM7 TSHR 4850/4885ALDH1A1 3276/4885ABCC4 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.