Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499561 | 1.00 | KDM4E (0.47) | KDM4EGLAPOLBTACR3L3MBTL1 | |
| SCHEMBL7018652 | 0.83 | SLC7A5 (0.55) | KDM4EGLAALDH1A1GAAHPGD | |
| SCHEMBL6495560 | 0.77 | LOXL2 (0.47) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6495563 | 0.76 | LOXL2 (0.46) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6495555 | 0.76 | LOXL2 (0.46) | KDM4EALDH1A1 | |
| Phenylalanine Methyl Ester SCHEMBL74888 | 0.76 | SLC7A5 (0.63) | ALDH1A1KMT2A | |
| Phenylalanine Methyl Ester SCHEMBL27880854 | 0.76 | SLC7A5 (0.63) | ALDH1A1KMT2A | |
| Phenylalanine Methyl Ester SCHEMBL74887 | 0.76 | SLC7A5 (0.63) | ALDH1A1KMT2A | |
| Phenylalanine Methyl Ester SCHEMBL186022 | 0.76 | SLC7A5 (0.63) | ALDH1A1KMT2A | |
| SCHEMBL27484851 | 0.75 | CYP1A2 (0.51) | ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716852-B2 | FOR THERAPY OF ARTERIAL HYPERTENSION AND CARDIOVASCULAR DISEASES | LES LABORATORIES SERVIER (FR) | 2004-04-06 | — | — | US | disclosed |
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | LES LABORATOIRES SERVIER (FR) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055086-A1 | Amino acid derivatives and use thereof as nep, ace and ece inhibitors | MME, ACE, ECE1 | KDM4E 592/4885GLA 1982/4885POLB 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.