Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | XIAP | P98170 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499561 | 0.83 | KDM4E (0.47) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL6774643 | 0.83 | KDM4E (0.47) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL12434729 | 0.83 | ALPI (0.55) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL180266 | 0.83 | ALPI (0.55) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL29407854 | 0.83 | ALPI (0.55) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL887084 | 0.83 | ALPI (0.55) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL13410459 | 0.76 | PKM (0.62) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL503050 | 0.76 | LOXL2 (0.53) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL1662034 | 0.76 | LOXL2 (0.53) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL29556980 | 0.76 | LOXL2 (0.53) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255757-B1 | AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS | INST NAT SANTE RECH MED (FR) | 2003-06-18 | — | — | EP | disclosed |
| EP-1255757-A1 | AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060822-A1 | AMINO ACID DERIVATIVES AND USE THEREOF AS NEP, ACE AND ECE INHIBITORS | INSTITUT NATIONAL DE LA RECHERCHE MEDICALE INSERM (FR) | 2001-08-23 | — | — | WO | disclosed |