⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717823 | 1.00 | — | — | |
| SCHEMBL1430963 | 1.00 | — | — | |
| SCHEMBL12449635 | 0.87 | KDM4E (0.51) | — | |
| SCHEMBL13003 | 0.87 | KDM4E (0.51) | — | |
| SCHEMBL2115306 | 0.87 | SIGMAR1 (0.41) | — | |
| SCHEMBL12449637 | 0.87 | KDM4E (0.51) | — | |
| SCHEMBL14685579 | 0.87 | SIGMAR1 (0.41) | — | |
| SCHEMBL91689 | 0.86 | CARM1 (0.56) | — | |
| SCHEMBL21786271 | 0.84 | KDM4E (0.49) | — | |
| SCHEMBL9374563 | 0.81 | SIGMAR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205648-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-3205648-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-2580210-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | SERAGON PHARMACEUTICALS INC (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2580210-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | SERAGON PHARMACEUTICALS INC (US) | 2017-03-01 | — | — | EP | disclosed |
| CN-102939287-B | Estrogenic agents and uses thereof | ARAGON PHARMACEUTICALS, INC. (US) | 2016-01-27 | — | — | CN | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-9078871-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS, INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-9078871-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS, INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-20130116232-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-20130116232-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| US-20130116232-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| CN-102939287-A | Estrogen receptor modulators and uses thereof | ARAGON PHARMACEUTICALS INC | 2013-02-20 | — | — | CN | disclosed |
| WO-2013018804-A1 | URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | 大日本住友製薬株式会社 (JP) | 2013-02-07 | — | — | WO | disclosed |
| WO-2011156518-A2 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | ARAGON PHARMACEUTICALS, INC. (US) | 2011-12-15 | — | — | WO | disclosed |
| US-6750213-B2 | BONE DISORDERS; UROGENITAL SYSTEM DISORDERS; ANTICANCER AGENTS | MERCK & CO., INC. | 2004-06-15 | — | — | US | disclosed |
| US-20030225132-A1 | Heterocyclic salts such as 3-(3-Hydroxyphenyl)-2-(4-(2-(1-pyrrolidinium)ethoxyphenol)-2,3-dihydro-1,4 -benzoxathiin-6-ol hydrochloride salt, used as estrane agonists, for phrophylaxis of bone disorders | DININNO FRANK P (US) | 2003-12-04 | — | — | US | disclosed |
| WO-2003086388-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| US-20020165226-A1 | Estrogen receptor modulators | MERCK & CO., INC. | 2002-11-07 | — | — | US | disclosed |