Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RHOC | P08134 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6770182 | 0.97 | NPC1 (0.42) | RAD52UBE2NL3MBTL1NPC1TRPV1 | |
| Trifluoroacetic Acid SCHEMBL6775993 | 0.89 | F10 (0.42) | RAD52UBE2NL3MBTL1NPC1TRPV1 | |
| Trifluoroacetic Acid SCHEMBL6890249 | 0.84 | F10 (0.49) | NPC1TRPV1F10RAB9APOLB | |
| Trifluoroacetic Acid SCHEMBL6769129 | 0.83 | F10 (0.53) | L3MBTL1RHOCRHOAF10ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6769455 | 0.82 | F10 (0.45) | F7NPC1F10 | |
| Trifluoroacetic Acid SCHEMBL6770318 | 0.82 | TRPV1 (0.42) | MAPTNPC1TRPV1F10HDAC6 | |
| Trifluoroacetic Acid SCHEMBL6771038 | 0.81 | ROCK1 (0.48) | F7F10 | |
| Trifluoroacetic Acid SCHEMBL6765882 | 0.81 | F10 (0.56) | NPC1F10ALDH1A1KLKB1KLK1 | |
| SCHEMBL6775235 | 0.80 | TBXAS1 (0.36) | F10ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6775615 | 0.80 | F10 (0.60) | L3MBTL1MAPTF10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |