Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 8/20 | 0.37 |
| ▸ | MET | P08581 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL6776480 | 0.85 | AXL (0.41) | AXLTRPA1KDRMETATM | |
| SCHEMBL6776169 | 0.82 | ATM (0.42) | KDRATM | |
| SCHEMBL6776483 | 0.82 | TRPA1 (0.39) | AXLTRPA1KDRMETEGFR | |
| SCHEMBL6780330 | 0.76 | KDR (0.39) | KDRATMEGFR | |
| SCHEMBL4374479 | 0.71 | AXL (0.56) | AXLTRPA1KDRMETATM | |
| SCHEMBL4422009 | 0.70 | TRPA1 (0.52) | TRPA1KDRMETEGFR | |
| SCHEMBL6776477 | 0.69 | TRPA1 (0.40) | TRPA1KDRMETEGFRFLT3 | |
| SCHEMBL4424010 | 0.69 | TRPA1 (0.46) | TRPA1KDRMETCCNT1CDK9 | |
| SCHEMBL4424729 | 0.69 | TRPA1 (0.57) | AXLTRPA1KDRMETEGFR | |
| SCHEMBL4686840 | 0.68 | TRPA1 (0.49) | TRPA1KDRMETEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806274-B1 | IMMUNOREGULATION OR IMMUNOSUPPRESSIVE AGENTS; TYROSINE KINASE INHIBITORS; PREVENTING ORGAN TRANSPLANT REJECTION; AUTOIMMUNE CONDITIONS; REDUCED SIDE EFFECTS | ASTRAZENECA UK LIMITED (GB) | 2004-10-19 | — | — | US | disclosed |