Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775538 | 0.85 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL6771753 | 0.85 | HTT (0.44) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL4031912 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL4030328 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL6205935 | 0.78 | TDP1 (0.51) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL21051836 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4ALOX15MAPT | |
| SCHEMBL6771507 | 0.78 | MAPT (0.46) | ALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL6776372 | 0.78 | ADRB2 (0.41) | ALDH1A1MAPTSMN1; SMN2KMT2AMAOA | |
| SCHEMBL6776375 | 0.78 | ADRB2 (0.41) | ALDH1A1MAPTSMN1; SMN2KMT2AMAOA | |
| SCHEMBL12302449 | 0.77 | KDM4E (0.42) | MAPTKMT2ASORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693123-B2 | (4-(3-PYRIDYLAMINOMETHYLENE)-2-PHENYLBENZOYL)-N -METHYLMETHIONINE, METHYL ESTER FOR EXAMPLE; RESTENOSIS, HYPERPLASIA | UNIVERSITY OF PITTSBURGH | 2004-02-17 | — | — | US | disclosed |
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | UNIVERSITY OF PITTSBURGH (US) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193596-A1 | Inhibitors of protein isoprenyl transferases | LANCL1, FNTB, DHCR7 | ALDH1A1 1121/4885TDP1 3740/4885CYP3A4 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.