SCHEMBL677712

SCHEMBL677712

CCCCC/C=C\C=C\C(O)CCCCCCCC(=O)OC

nearest known ligand 0.86

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.73
GPR132 Q9UNW8 1/20 0.73
FAAH O00519 1/20 0.66
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
LTB4R2 Q9NPC1 1/20 0.55
ALOX5 P09917 1/20 0.55
MAPT P10636 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676737 1.00 PPARG (0.73) PPARGGPR132FAAHMEN1KMT2A
SCHEMBL31359284 1.00 PPARG (0.73) PPARGGPR132FAAHMEN1KMT2A
SCHEMBL677201 1.00 PPARG (0.73) PPARGGPR132FAAHMEN1KMT2A
SCHEMBL18045215 1.00 PPARG (0.73) PPARGGPR132FAAHMEN1KMT2A
SCHEMBL6288019 1.00 PPARG (0.73) PPARGGPR132FAAHMEN1KMT2A
SCHEMBL13443444 0.95 PPARG (0.65) PPARGGPR132FAAHLTB4R2ALOX5
SCHEMBL10027752 0.95 PPARG (0.65) PPARGGPR132FAAHLTB4R2ALOX5
SCHEMBL29536611 0.90 PPARG (0.58) PPARGGPR132FAAHMEN1KMT2A
SCHEMBL19181457 0.89 PPARG (0.73) PPARGGPR132FAAHMEN1KMT2A
SCHEMBL22625520 0.89 PPARG (0.57) PPARGGPR132FAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160264979-A1 Methods for Controlling Flower Development in Plants UNIV YALE (US) 2016-09-15 US disclosed
US-9258998-B2 Methods for controlling flower development in plants YALE UNIVERSITY (US) 2016-02-16 US disclosed
US-20120010077-A1 Methods for Controlling Flower Development in Plants YALE UNIVERSITY 2012-01-12 US disclosed
WO-2010081005-A1 METHOD FOR CONTROLLING FLOWER DEVELOPMENT IN PLANTS YALE UNIVERSITY (US) 2010-07-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264979-A1 Methods for Controlling Flower Development in Plants CYP17A1, STOM, ERG28 PPARG 1536/4885GPR132 4421/4885FAAH 460/4885
US-20120010077-A1 Methods for Controlling Flower Development in Plants CYP17A1, STOM, ERG28 PPARG 1536/4885GPR132 4421/4885FAAH 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.