Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.65 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 3/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13443444 | 1.00 | PPARG (0.65) | PPARGGPR132FAAHLTB4RALOX5 | |
| SCHEMBL6288019 | 0.95 | PPARG (0.73) | PPARGGPR132FAAHALOX5MAPT | |
| SCHEMBL677201 | 0.95 | PPARG (0.73) | PPARGGPR132FAAHALOX5MAPT | |
| SCHEMBL676737 | 0.95 | PPARG (0.73) | PPARGGPR132FAAHALOX5MAPT | |
| SCHEMBL31359284 | 0.95 | PPARG (0.73) | PPARGGPR132FAAHALOX5MAPT | |
| SCHEMBL18045215 | 0.95 | PPARG (0.73) | PPARGGPR132FAAHALOX5MAPT | |
| SCHEMBL677712 | 0.95 | PPARG (0.73) | PPARGGPR132FAAHALOX5MAPT | |
| SCHEMBL29927130 | 0.90 | ALOX5 (0.74) | FAAHALOX5MAPTLTB4R2 | |
| SCHEMBL14951386 | 0.90 | LTB4R (0.74) | PPARGGPR132FAAHLTB4RALOX5 | |
| SCHEMBL10868740 | 0.89 | FPR2 (0.58) | PPARGGPR132FAAHLTB4RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355562-A1 | METHODS FOR STABILIZING ATHEROSCLEROTIC PLAQUES USING LIPOXINS, RESOLVINS, AND ANALOGS THEREOF | ADA FORSYTH INSTITUTE, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20180078519-A1 | Methods for Stabilizing Atherosclerotic Plaques Using Lipoxins, Resolvins, and Analogs Thereof | THE FORSYTH INSTITUTE (US) | 2018-03-22 | — | — | US | disclosed |
| US-8093417-B2 | Lipoxin analogs and methods for the treatment of periodontal disease | TRUSTEES OF BOSTON UNIVERSITY (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110064677-A1 | LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE | TRUSTEES OF BOSTON UNIVERSITY (US) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064677-A1 | LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE | ALOX5, ALOX15B, ALOX12 | PPARG 112/4885GPR132 2259/4885FAAH 331/4885 |
| US-20230355562-A1 | METHODS FOR STABILIZING ATHEROSCLEROTIC PLAQUES USING LIPOXINS, RESOLVINS, AND ANALOGS THEREOF | ALOX15B, ALOX15, ALOX5 | PPARG 214/4885GPR132 3870/4885FAAH 112/4885 |
| US-20180078519-A1 | Methods for Stabilizing Atherosclerotic Plaques Using Lipoxins, Resolvins, and Analogs Thereof | ALOX15B, ALOX15, ALOX5 | PPARG 214/4885GPR132 3870/4885FAAH 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.