SCHEMBL677719

SCHEMBL677719

CC(C)(c1ccc(O[PH](=O)Oc2ccccc2)cc1)c1ccc(OP(=O)(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
SRC P12931 1/20 0.37
ALDH1A1 P00352 6/20 0.37
KDM4E B2RXH2 6/20 0.36
POLB P06746 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218852 0.89 CYP3A4 (0.50) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL25513744 0.89 CYP3A4 (0.50) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL9910592 0.89 SMN1; SMN2 (0.45) CYP3A4MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL6472688 0.87 CYP3A4 (0.48) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL1548707 0.87 CYP3A4 (0.48) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL9332956 0.85 CYP3A4 (0.50) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL14959823 0.85 CYP3A4 (0.36) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL9910584 0.83 CA4 (0.47) CYP3A4MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL15257114 0.83 PKM (0.51) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL9906996 0.83 CYP3A4 (0.44) CYP3A4TSHRMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2868694-A1 CELLULOSE ESTER-BASED RESIN COMPOSITION Adeka Corporation (JP) 2015-05-06 EP disclosed
US-20140155528-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED PRODUCT MADE THEREOF TORAY INDUSTRIES, INC. (JP) 2014-06-05 US disclosed
US-8440748-B2 Thermoplastic resin composition and molded item formed from same TORAY INDUSTRIES, INC. (JP) 2013-05-14 US disclosed
US-20120329920-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ITEM FORMED FROM SAME TORAY INDUSTRIES, INC. (JP) 2012-12-27 US disclosed
US-7863382-B2 Resin composition and molded article comprising the same Toray Industriés, Inc. (JP) 2011-01-04 US disclosed
US-20080262151-A1 Resin Composition and Molded Article Comprising the Same TORAY INDUSTRIES, INC. (JP) 2008-10-23 US disclosed