Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778341 | 0.88 | TLR7 (0.35) | TLR7EPHX2TLR8NUDT1 | |
| SCHEMBL6774067 | 0.87 | ALDH1A1 (0.39) | TLR7TLR8ALDH1A1NUDT1 | |
| SCHEMBL6777973 | 0.87 | TLR7 (0.37) | TLR7TLR8NUDT1 | |
| SCHEMBL6772831 | 0.87 | FAAH (0.38) | TLR7TLR8ALDH1A1NUDT1 | |
| SCHEMBL6776588 | 0.86 | EPHX2 (0.37) | GAATLR7EPHX2TLR8NUDT1 | |
| SCHEMBL6773840 | 0.85 | TLR7 (0.37) | TLR7TLR8ALDH1A1NUDT1 | |
| SCHEMBL6777299 | 0.85 | ALDH1A1 (0.43) | KDM4EMAPTGAATLR7TLR8 | |
| SCHEMBL6288252 | 0.84 | EPHX2 (0.47) | EPHX2 | |
| SCHEMBL6093363 | 0.84 | TLR7 (0.36) | TLR7TLR8NUDT1 | |
| SCHEMBL6288804 | 0.82 | TLR7 (0.41) | KDM4EGAATLR7TLR8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |