Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.58 |
| ▸ | RXRB | P28702 | 3/20 | 0.58 |
| ▸ | RXRG | P48443 | 3/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440031 | 0.85 | FFAR1 (0.55) | RXRARXRBRXRGTHRATHRB | |
| SCHEMBL491539 | 0.84 | ABCC4 (0.52) | RXRARXRBRXRGPTGDR2PPARD | |
| SCHEMBL491853 | 0.83 | PTGS1 (0.58) | RXRARXRBRXRGPTGDR2PPARD | |
| SCHEMBL6367068 | 0.81 | PTGS1 (0.51) | RXRARXRBRXRGPTGS1AKR1C3 | |
| SCHEMBL3572558 | 0.81 | PPARD (0.53) | PPARDMEN1KMT2A | |
| SCHEMBL347352 | 0.79 | PTGS1 (0.59) | RXRARXRBRXRGPTGS1AKR1C3 | |
| SCHEMBL4430445 | 0.78 | ACLY (0.43) | RXRARXRBRXRGPTGDR2CYP11B1 | |
| Hydrochloric Acid SCHEMBL2531690 | 0.77 | PTGS1 (0.58) | RXRARXRBRXRGPTGS1AKR1C3 | |
| SCHEMBL29746063 | 0.77 | ABCC4 (0.44) | RXRARXRBRXRGPTGDR2PPARD | |
| SCHEMBL3569849 | 0.77 | PPARD (0.56) | RXRARXRBRXRGPPARDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014176460-A1 | METHODS OF TREATING BEHAVIORIAL AND/OR MENTAL DISORDERS | CHAU DAVID T (US) | 2014-10-30 | — | — | WO | disclosed |
| US-8486922-B2 | Composition | CHEN CHIEN-HUNG (TW) | 2013-07-16 | — | — | US | disclosed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | disclosed |
| US-20110281829-A1 | NOVEL COMPOSITION | IPINTL, LLC (US) | 2011-11-17 | — | — | US | disclosed |