Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470491 | 0.88 | DYRK1A (0.70) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29443248 | 0.88 | CYP2D6 (0.72) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL67779 | 0.88 | CYP2D6 (0.72) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| Phosphine SCHEMBL17375055 | 0.87 | CYP2D6 (0.70) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24938765 | 0.85 | DYRK1A (1.00) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL67273 | 0.78 | MCL1 (0.47) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31344274 | 0.78 | MCL1 (0.47) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7115071 | 0.78 | ALDH1A1 (1.00) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15842463 | 0.78 | KDM4E (0.71) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29975674 | 0.77 | CYP2D6 (0.68) | DYRK1AKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5000945-A | — | — | None | — | — | JP | disclosed |
| US-5716983-A | ADMINISTERING PHOSPHOLIPASE INHIBITOR FOR TREATMENT OF INFLAMMATORY DISEASES, ALLERGIES, INJURIES, CARDIOVASCULAR DISORDERS, AUTOIMMUNE DISORDERS OR TRANSPLANT REJECTION | BOEHRINGER MANNHEIM GMBH (DE) | 1998-02-10 | — | — | US | disclosed |
| JP-H05945-A | CARCINOSTATIC AGENT | NIKKO KYODO CO LTD | 1993-01-08 | — | — | JP | disclosed |