Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790600 | 0.88 | TLR8 (0.37) | TLR7TLR8 | |
| SCHEMBL6784344 | 0.87 | TLR7 (0.40) | TLR7TLR8KCNH2PIK3CA | |
| SCHEMBL4793247 | 0.87 | TLR8 (0.37) | TLR7TLR8 | |
| SCHEMBL4791859 | 0.87 | TLR8 (0.38) | TLR7TLR8 | |
| SCHEMBL6774337 | 0.85 | TLR8 (0.39) | TLR7TLR8PIK3CALMNA | |
| SCHEMBL6778344 | 0.84 | TLR7 (0.36) | TLR7TLR8KCNH2KAT6APIK3CA | |
| SCHEMBL6783284 | 0.84 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6778425 | 0.84 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL6778433 | 0.83 | TLR7 (0.47) | TLR7TLR8LMNA | |
| SCHEMBL6778051 | 0.83 | TLR7 (0.46) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |