Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778051 | 0.86 | TLR7 (0.46) | TLR7TLR8NUDT1HTR7 | |
| SCHEMBL6778433 | 0.85 | TLR7 (0.47) | TLR7TLR8NUDT1HTR7 | |
| SCHEMBL6778097 | 0.84 | TLR7 (0.38) | TLR7TLR8 | |
| SCHEMBL6783227 | 0.83 | TLR7 (0.39) | TLR7TLR8NUDT1HTR7 | |
| SCHEMBL6783864 | 0.82 | TLR7 (0.45) | TLR7TLR8NUDT1 | |
| SCHEMBL6778425 | 0.82 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6779031 | 0.81 | TLR7 (0.42) | TLR7HTR7 | |
| SCHEMBL6285401 | 0.81 | TLR7 (0.52) | TLR7TLR8NUDT1 | |
| SCHEMBL6774751 | 0.81 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6784344 | 0.81 | TLR7 (0.40) | TLR7TLR8HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |