Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | FGB | P02675 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779818 | 0.94 | POLB (0.48) | ALDH1A1LMNAGAASMN1; SMN2HTR7 | |
| SCHEMBL6773797 | 0.89 | KMT2A (0.43) | ALDH1A1LMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL6778251 | 0.87 | MEN1 (0.43) | ALDH1A1LMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL6780037 | 0.85 | CYP3A4 (0.40) | ALDH1A1MEN1KMT2AUSP2ESR1 | |
| SCHEMBL6779292 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6774446 | 0.85 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2USP2HTR7 | |
| SCHEMBL6778259 | 0.83 | KDM4E (0.39) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL6779678 | 0.82 | NPY5R (0.40) | MEN1KMT2AUSP2ESR1CYP1A2 | |
| SCHEMBL6778198 | 0.82 | CA1 (0.40) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6780566 | 0.82 | CYP3A4 (0.45) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |