Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778211 | 0.94 | ALDH1A1 (0.50) | POLBHTR7ALDH1A1LMNAGAA | |
| SCHEMBL6774423 | 0.87 | TLR7 (0.41) | HTR7ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL6775218 | 0.86 | POLB (0.42) | POLBHTR7ALDH1A1LMNAGAA | |
| SCHEMBL6779264 | 0.86 | ALDH1A1 (0.41) | POLBHTR7ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL6779845 | 0.83 | KDM4E (0.38) | POLB | |
| SCHEMBL6777386 | 0.83 | CCR1 (0.41) | HTR7ALDH1A1HTR1AHTR2AHTR2C | |
| SCHEMBL6779812 | 0.83 | SCN1A (0.48) | HTR7ALDH1A1HTR1AHTR2AHTR6 | |
| SCHEMBL6773797 | 0.83 | KMT2A (0.43) | POLBHTR7ALDH1A1LMNAGAA | |
| SCHEMBL6778251 | 0.81 | MEN1 (0.43) | ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL6780037 | 0.80 | CYP3A4 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |