Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 2/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206491 | 0.92 | DTYMK (0.49) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL5539153 | 0.78 | CHRM2 (0.56) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL23536559 | 0.77 | PIK3CD (0.47) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL3985708 | 0.75 | MEN1 (0.55) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL15265090 | 0.75 | GAA (0.56) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL3968708 | 0.75 | USP2 (0.49) | DDB1CRBNUSP2SMN1; SMN2ALDH1A1 | |
| SCHEMBL734678 | 0.75 | DDB1 (0.44) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL4068455 | 0.75 | KMT2A (0.42) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL1571128 | 0.75 | USP2 (0.43) | DTYMKDDB1CRBNCHRM2CHRM4 | |
| SCHEMBL18294 | 0.75 | USP2 (0.69) | USP2SMN1; SMN2ALDH1A1GPR119MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208089-B1 | DIAZOCIN-DIONE DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS | ALTANA PHARMA AG (DE) | 2004-10-13 | — | — | EP | disclosed |
| US-6673786-B1 | TREATING ALLERGIC OR INFLAMMATORY DISORDERS | ALTANA PHARMA AG (DE) | 2004-01-06 | — | — | US | disclosed |