Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779411 | 1.00 | DRD2 (0.42) | DRD2DRD3TLR7SIGMAR1TLR8 | |
| SCHEMBL6287386 | 0.88 | TLR7 (0.40) | TLR7TLR8NUDT1 | |
| SCHEMBL6111303 | 0.86 | TLR7 (0.43) | DRD2DRD3TLR7SIGMAR1TLR8 | |
| SCHEMBL6111300 | 0.86 | TLR7 (0.43) | DRD2DRD3TLR7SIGMAR1TLR8 | |
| SCHEMBL6093721 | 0.85 | SIGMAR1 (0.41) | DRD2DRD3TLR7SIGMAR1TLR8 | |
| SCHEMBL6093725 | 0.85 | SIGMAR1 (0.41) | DRD2DRD3TLR7SIGMAR1TLR8 | |
| SCHEMBL6774169 | 0.84 | TLR7 (0.39) | DRD2TLR7TLR8ALDH1A1 | |
| SCHEMBL6775141 | 0.83 | TLR7 (0.51) | DRD2DRD3TLR7TLR8NUDT1 | |
| SCHEMBL6773964 | 0.82 | TP53 (0.42) | — | |
| SCHEMBL6773648 | 0.82 | TLR7 (0.48) | TLR7TLR8NUDT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |