Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784448 | 0.82 | SMN1; SMN2 (0.38) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL6364141 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL7212663 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTNPC1ALDH3A1ALDH1A3 | |
| SCHEMBL498799 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL6777845 | 0.70 | EPHX2 (0.41) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL5057067 | 0.69 | ALDH1A1 (0.58) | ALDH1A1KDM4EALDH3A1ALDH1A3NPSR1 | |
| SCHEMBL6364681 | 0.68 | ALDH1A1 (0.48) | ALDH1A1ADRB2ADRB1ADRB3EPHX2 | |
| SCHEMBL6780983 | 0.68 | ALDH1A1 (0.44) | ALDH1A1MAPTADRB3ALDH1A3KMT2A | |
| SCHEMBL1185621 | 0.66 | ALDH1A1 (0.63) | ALDH1A1MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL16569010 | 0.66 | TYR (0.46) | ALDH1A1MAPTNPC1RAB9AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176445-A1 | Propionic acid derivatives | BAYER PHARMACEUTICALS CORPORATION | 2004-09-09 | — | — | US | disclosed |
| US-6750236-B2 | CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20030187041-A1 | Propionic acid derivatives | URBAHNS KLAUS (DE) | 2003-10-02 | — | — | US | disclosed |
| US-6548538-B2 | Potent peroxisome proliferator activated receptor (PPAR)-alpha-activating compounds; propionic acid 2-subsituted with an N-(phenylaminocarbonylalkyl), N-(2-furanylmethyl)aminoalkylphenyl group | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-15 | — | — | US | disclosed |
| US-20030032671-A1 | Propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187041-A1 | Propionic acid derivatives | PPARA, PPARD, PPARG | ALDH1A1 257/4885MAPT 4388/4885KDM4E 3413/4885 |
| US-20030032671-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | ALDH1A1 550/4885MAPT 4503/4885KDM4E 4055/4885 |
| US-20040176445-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | ALDH1A1 550/4885MAPT 4503/4885KDM4E 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.