Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31211326 | 0.78 | SMN1; SMN2 (0.40) | RAB9AALDH1A1GAAMAPTKMT2A | |
| SCHEMBL9323836 | 0.76 | AR (0.56) | RAB9AALDH1A1PDE1CGAAMAPT | |
| SCHEMBL1417348 | 0.74 | AR (0.54) | ALDH1A1LMNAMAPTKMT2AAR | |
| SCHEMBL8100794 | 0.73 | MAPT (0.42) | ALDH1A1GAALMNAMAPTKMT2A | |
| SCHEMBL6348211 | 0.71 | RAB9A (0.64) | RAB9AALDH1A1PDE1CGAALMNA | |
| SCHEMBL6779141 | 0.69 | GAA (0.42) | ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL22694071 | 0.69 | ALDH1A1 (0.66) | RAB9AALDH1A1PDE1CGAALMNA | |
| SCHEMBL6179663 | 0.69 | AR (0.42) | ALDH1A1LMNAMAPTKMT2AAR | |
| SCHEMBL14876173 | 0.68 | LPAR3 (0.54) | LMNAKMT2A | |
| SCHEMBL22946414 | 0.68 | SMN1; SMN2 (0.52) | RAB9AALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683189-B1 | POLYAMIDE-OLIGONUCLEOTIDE CONJUGATES; NETROPSIN AND DISTAMYCIN A SYNTHESIS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-01-27 | — | — | US | disclosed |
| US-6545162-B1 | Solid phase biosynthesis of viricide antibiotic | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-04-08 | — | — | US | disclosed |
| EP-0885189-B9 | METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT | CALIFORNIA INST OF TECHN (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6090947-A | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-07-18 | — | — | US | disclosed |