Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.57 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | PRKX | P51817 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.57 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.57 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209853 | 0.82 | ROCK2 (0.52) | KMT2AMMP13ROCK2SMN1; SMN2RAB9A | |
| SCHEMBL27833527 | 0.80 | KMT2A (0.70) | KMT2AMMP13ROCK2ROCK1RPS6KA5 | |
| SCHEMBL30780061 | 0.79 | HPGD (0.77) | KMT2AMMP13ROCK2ROCK1RPS6KA5 | |
| SCHEMBL1568246 | 0.79 | SMN1; SMN2 (0.68) | KMT2AROCK2MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL1568699 | 0.79 | NAMPT (0.69) | KMT2AMMP13ROCK2ROCK1RPS6KA5 | |
| SCHEMBL1568387 | 0.79 | HPGD (0.77) | KMT2AMMP13ROCK2ROCK1RPS6KA5 | |
| SCHEMBL4658947 | 0.79 | KMT2A (0.68) | KMT2AMMP13ROCK2ROCK1RPS6KA5 | |
| SCHEMBL27833534 | 0.78 | KMT2A (0.63) | KMT2AMMP13ROCK2ROCK1RPS6KA5 | |
| SCHEMBL1569194 | 0.78 | ROCK2 (0.82) | KMT2AMMP13ROCK2ROCK1RPS6KA5 | |
| SCHEMBL5883325 | 0.77 | KMT2A (0.55) | KMT2ASMN1; SMN2RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780883-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS | WARNER-LAMBERT COMPANY | 2004-08-24 | — | — | US | disclosed |