Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784970 | 0.86 | HDAC4 (0.41) | KDM4ETDP1SLC22A12S1PR1DHODH | |
| SCHEMBL6781999 | 0.83 | DHODH (0.46) | KDM4ETDP1S1PR1DHODHHDAC6 | |
| SCHEMBL6780315 | 0.78 | ALDH1A1 (0.42) | KDM4ES1PR1DHODHPLATS1PR3 | |
| SCHEMBL14717695 | 0.75 | GAA (0.41) | ABL1PLAT | |
| SCHEMBL14717699 | 0.75 | GAA (0.41) | ABL1PLAT | |
| SCHEMBL15236975 | 0.74 | S1PR1 (0.48) | SLC22A12S1PR1HDAC6HDAC1HDAC8 | |
| SCHEMBL14717479 | 0.73 | ITGA4 (0.44) | NPC1POLB | |
| SCHEMBL14717483 | 0.73 | ITGA4 (0.44) | NPC1POLB | |
| SCHEMBL6782045 | 0.73 | AKR1B1 (0.48) | KDM4ETDP1S1PR1DHODHHDAC6 | |
| SCHEMBL6786662 | 0.72 | HDAC4 (0.44) | KDM4ETDP1SLC22A12S1PR1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699853-B2 | PROTECTING USEFUL PLANTS AGAINST THE UNDESIRABLE ACTION OF HARMFUL INSECTS, ACARIDS AND NEMATODES, | HOECHST SCHERING AGREVO GMBH (DE) | 2004-03-02 | — | — | US | disclosed |