Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 7/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780566 | 0.94 | CYP3A4 (0.45) | SCN1ASCN2ASCN3AKDM4EALDH1A1 | |
| SCHEMBL6779715 | 0.86 | TLR7 (0.45) | SCN1ASCN2ASCN3AKDM4EALDH1A1 | |
| SCHEMBL6779818 | 0.83 | POLB (0.48) | ALDH1A1NPY5RHTR7HTR6DRD2 | |
| SCHEMBL6774423 | 0.82 | TLR7 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6777563 | 0.81 | SCN1A (0.49) | SCN1ASCN2ASCN3AKDM4EALDH1A1 | |
| SCHEMBL6779264 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C19HTR7TLR7 | |
| SCHEMBL6780266 | 0.80 | CYP2C9 (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6778418 | 0.79 | TLR7 (0.39) | TLR7 | |
| SCHEMBL6287590 | 0.79 | TLR7 (0.46) | ALDH1A1TLR7 | |
| SCHEMBL6773797 | 0.79 | KMT2A (0.43) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696465-B2 | INDUCING BIOSYNTHESIS OF CYTOKINES; VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-24 | — | — | US | claimed |