Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309154 | 0.95 | PTGS2 (0.55) | PTGS2PTGS1PRKCZ | |
| SCHEMBL6781474 | 0.90 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6309362 | 0.88 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6780056 | 0.87 | PTGS2 (0.44) | PTGS2PTGS1PRKCZ | |
| SCHEMBL6309247 | 0.86 | ALOX5 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6315413 | 0.86 | PTGS2 (0.45) | PTGS2PTGS1PRKCZ | |
| SCHEMBL6315480 | 0.85 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL6314423 | 0.84 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL6315520 | 0.83 | ALOX5 (0.41) | PTGS2PTGS1 | |
| SCHEMBL6314768 | 0.83 | PTGS2 (0.57) | PTGS2PTGS1PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753344-B2 | SULFONYL OR SULFONAMIDE SUBSTITUTED BENZENE DERIVATIVE CONTAINING HYDROXYUREA GROUP; USEFUL AS ANTIINFLAMMATORY AGENT | PHARMACIA CORPORATION | 2004-06-22 | — | — | US | claimed |