Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | APAF1 | O14727 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780376 | 1.00 | KDM4E (0.55) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL12986273 | 0.83 | KDM4E (0.56) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL18383119 | 0.79 | NR4A2 (0.56) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL29579851 | 0.79 | NR4A2 (0.56) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL19585950 | 0.79 | KDM4E (0.52) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL6555702 | 0.78 | NR4A2 (0.55) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL13203774 | 0.78 | NR4A2 (0.55) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL2184960 | 0.78 | NR4A2 (0.55) | KDM4ENR4A2IDO1KMT2AMEN1 | |
| SCHEMBL6655810 | 0.76 | IDO1 (0.53) | KDM4EIDO1KMT2AMEN1APAF1 | |
| SCHEMBL6655804 | 0.76 | IDO1 (0.53) | KDM4EIDO1KMT2AMEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784323-B2 | Enantioselective transformation of α,β-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-08-31 | — | — | US | disclosed |
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | ALDH1A1, GAR1, ALDH1B1 | KDM4E 2340/4885NR4A2 1104/4885IDO1 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.